Aviremia 10 Years Postdiscontinuation of Antiretroviral Therapy Initiated During Primary Human Immunodeficiency Virus-1 Infection and Association With Gag-Specific T-Cell Responses

نویسندگان

  • Sabine Kinloch-de Loes
  • Lucy Dorrell
  • Hongbing Yang
  • Gareth A. D. Hardy
  • Sabine Yerly
  • Cristina Cellerai
  • Linos Vandekerckhove
  • Ward De Spielgelaere
  • Eva Malatinkova
  • Willie Wee Lee Koh
  • Margaret A. Johnson
چکیده

Combination antiretroviral therapy during primary human immunodeficiency virus-1 infection may enable long-term drug-free virological control in rare individuals. We describe a female who maintained aviremia and a normal CD4(+)/CD8(+) T cell ratio for 10 years after stopping therapy, despite a persistent viral reservoir. Cellular immune responses may have contributed to this outcome.

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عنوان ژورنال:

دوره 2  شماره 

صفحات  -

تاریخ انتشار 2015